Advanced Data Mining Technologies in Bioinformatics by Hui-Huang Hsu

By Hui-Huang Hsu

The applied sciences in facts mining were effectively utilized to bioinformatics learn some time past few years, yet extra examine during this box is critical. whereas large growth has been revamped the years, the various primary demanding situations in bioinformatics are nonetheless open. information mining performs a vital position in figuring out the rising difficulties in genomics, proteomics, and structures biology. complex info Mining applied sciences in Bioinformatics covers very important examine themes of knowledge mining on bioinformatics. Readers of this booklet will achieve an realizing of the fundamentals and difficulties of bioinformatics, in addition to the functions of knowledge mining applied sciences in tackling the issues and the basic study issues within the box. complex facts Mining applied sciences in Bioinformatics is intensely precious for info mining researchers, molecular biologists, graduate scholars, and others drawn to this subject.

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Paley, S. , & Pellegrini-Toole, A. (2000). The EcoCyc and MetaCyc databases. Nucleic Acids Research, 28, 56-59. , Mian, I. , & Haussler, D. (1994). Hidden Markov models in computational biology: Applications to protein modeling. Journal of Molecular Biology, 235, 1501-1531. , & Tomb, J-F. (2002). Genome comparisons based on profiles of metabolic pathways”, In The Proceedings of The Sixth International Conference on Knowledge-Based Intelligent Information & Engineering Systems (pp. 469-476). Crema, Italy: IOS Press.

Genomics, 19, 97-107. , & Singh, A. J. (2003). Deriving phylogenetic trees from the similarity analysis of metabolic pathways. Bioinformatics, 19, i138-i146. , & Jeong, H. (2003). Subnetwork hierarchies of biochemical pathways. Bioinformatics, 19, 532-538. , & Haussler, D. (1999). Using the Fisher Kernel Method to detect remote protein homologies. In Proceedings of the Seventh International Conference on Intelligent Systems for Molecular Biology (pp. 149-158). Menlo Park, CA: AAAI Press. , & Haussler, D.

Definition 1 (a) Score Function: A score function s is a function from D to R in which the function s assigns a score (a real number) to each object in D. In a more formal way, we write s: D → R such that for every di in D, there exists a real number s(di) in R corresponding to di. (b) Rank Function: A rank function r is a function from D to N such that the function r : D → N maps each element di in D to a natural number r(di) in N. The number r(di) stands for the rank number r(di) assigned to the object di.

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