By Frank Entschladen, Kurt S. Zanker
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Extra resources for Cell Migration: Signalling and Mechanisms (Translational Research in Biomedicine, Vol. 2)
The maintenance of polarity is essential for all movement. Polarity is achieved by the differential recruitment of chemoattractant and specific adhesion receptors (chemokine and integrin receptors) at the front of the cell, where actinrich structures such as filopodia, pseudopodia and the leading lamella protrude (fig. 2). In contrast, the microtubule-organizing center (MTOC), Golgi apparatus (GA) and associated vesicles are directed backwards to the uropod (fig. 2). Much work is Endothelial cells Blood flow UP LE Tethering and rolling Firm adhesion and docking structure Polarization Migration Gradient origin Diapedesis Fig.
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