Chemokines and Viral Infection (Current Topics in by T.E. Lane (Editor)

By T.E. Lane (Editor)

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Extra resources for Chemokines and Viral Infection (Current Topics in Microbiology and Immunology)

Sample text

38 34 34 35 36 References . . . . . . . . . . . . . . . . . . . . . . . . . 40 Abstract The complex interplays between cytokines and chemokines are emerging as key communication signals in the shaping of innate and adaptive immune responses against foreign pathogens, including viruses. In particular, the virus-induced expression of cytokine and chemokine profiles drives the recruitment and activation of immune effector cells to sites of tissue infection. Under the conditions of infection with murine cytomegalovirus (MCMV), a herpesvirus with pathogenic potential, early immune functions are essential in the control of virus replication and virus-induced pathology.

Reddehase MJ, Mutter W, Munch K, Buhring HJ, Koszinowski UH (1987) CD8positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity. J Virol 61:3102–3108 Cytokine and Chemokine Networks: Pathways to Antiviral Defense 45 71. Ritz J, Campen TJ, Schmidt RE, Royer HD, Hercend T, Hussey RE, Reinhertz EL (1985) Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones. Science 228:1540–1543 72. Rollins BJ (1996) Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease.

Zhou Y, Kurihara T, Ryseck RP, Yang Y, Ryan C, Loy J, Warr G, Bravo R (1998) Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol 160:4018–4025 CTMI (2006) 303:29–46 c Springer-Verlag Berlin Heidelberg 2006 Cytokine and Chemokine Networks: Pathways to Antiviral Defense T. P. Salazar-Mather (✉) · K. L. edu 1 Introduction . . . . . . . . . . . . . . . . . . . . . . 2 NK Cells and Antiviral Defenses .

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